Fig. 3

A Top left. The color fundus photo of the right eye of a 33-year-old female with a history of BVMD. The macular area shows the characteristic yellowish vitelliform lesion and scattered subretinal dot hemorrhages (arrow). Note the cuff of neurosensory detachment (black arrowhead). Top right. SS-OCT in a line scan mode shows a subfoveal hyperreflective vitelliform lesion with surrounding neurosensory detachment and underlying irregular flat PED (double layer sign). CMT measures 374 µm. Bottom. SS-OCTA in a 3 × 3 mm field of the outer retina and the corresponding flow density map. Note the typical hyperintense signal of an active neovascular network that exhibits dense anastomosis and looping in a typical lacy-wheel pattern. B Top left. The color fundus photo 36 months after a single IVA injection. Note the resolution of the previously noted subretinal dot hemorrhages and neurosensory detachment. Top right. SS-OCT in a line scan mode of the same eye. The macular area shows resolution of neurosensory detachment and reduction in the size of the previously noted subfoveal vitelliform lesion. CMT measures 279 µm. Bottom. SS-OCTA image of the outer retina in a 3 × 3 mm field and the corresponding flow density map. Note the almost complete resolution of the previously noted CNV hyperintense signal with residual discrete vascular streaks and minimal blood flow