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Table 2 Comparison of choroidal parameters among IRD groups and healthy controls

From: Choroidal structure investigated by choroidal vascularity index in patients with inherited retinal diseases

 

RP

 

STGD

 

Cone- Rod Dystrophy

 

LCA

 

Usher Syndrome

 

Control

 

P-value*

Total Choroidal Area

2.24 ± 0.53

 

2.23 ± 0.35

 

2.29 ± 0.74

 

2.53 ± 0.97

 

2.62 ± 0.61

 

2.49 ± 0.5

 

< 0.001

Statistically significant different groups (P-value)**

Control (< 0.001)

         

RP (< 0.001)

  

Luminal Area

1.46 ± 0.38

 

1.44 ± 0.24

 

1.43 ± 0.5

 

1.57 ± 0.62

 

1.82 ± 0.46

 

1.78 ± 0.35

 

< 0.001

Statistically significant different groups (P-value)**

Control (< 0.001)

Usher Syndrome

(P = 0.045)

   

Control (0.015)

   

Usher Syndrome

(P = 0.045)

 

RP (< 0.001)

CRD (0.015)

  

CVI

0.65 ± 0.06

 

0.65 ± 0.06

 

0.62 ± 0.04

 

0.62 ± 0.04

 

0.69 ± 0.04

 

0.72 ± 0.04

 

< 0.001

Statistically significant different groups (P-value)**

Control (< 0.001)

   

Control (< 0.001)

Usher (0.005)

 

Control (0.003)

Usher (0.045)

 

CRD (0.005)

LCA (0.045)

 

RP (< 0.001)

CRD (< 0.001)

LCA (0.003)

  

Stromal Area

0.77 ± 0.22

 

0.79 ± 0.21

 

0.86 ± 0.25

 

0.96 ± 0.39

 

0.8 ± 0.2

 

0.7 ± 0.2

 

0.77

  1. IRD: Inherited Retinal Disease; RP: Retinitis Pigmentosa; STGD: Stargardt Disease; LCA: Leber Congenital Amaurosis; CVI: Choroidal Vascularity Index; CRD: Cone-rod dystrophy; * Based on general linear model; ** multiple comparisons considered by Bonferroni method. Adjusted P values have been reported