Table 2 Dark and light-adapted ERG responses at baseline and 12-week study visits
ERG stimulus | Measurement | Baseline | Follow-up | P (Paired t-test) |
|---|---|---|---|---|
DA—0.01 | b-wave amplitude (µV) | 195.6 ± 37.0 | 214.6 ± 28.9 | 0.5313 |
b-wave implicit time (ms) | 101.1 ± 3.7 | 102.1 ± 3.6 | 0.8158 | |
DA—3.0 | a-wave implicit time (ms) | 23.2 ± 0.8 | 23.1 ± 0.8 | 0.9052 |
a-wave amplitude (µV) | 148.3 ± 23.2 | 193.2 ± 23.7 | 0.1840 | |
b-wave implicit time (ms) | 65.3 ± 7.0 | 56.5 ± 1.4 | 0.2549 | |
b-wave amplitude (µV) | 371.6 ± 44.2 | 425.9 ± 36.5 | 0.1840 | |
OP AUC (µV.ms) | 483.9 ± 49.7 | 523.2 ± 117.5 | 0.5243 | |
DA—10.0 | a-wave implicit time (ms) | 17.7 ± 1.0 | 18.0 ± 0.9 | 0.7324 |
a-wave amplitude (µV) | 199.8 ± 27.8 | 233.9 ± 24.0 | 0.1511 | |
b-wave implicit time (ms) | 57.1 ± 1.8 | 60.5 ± 2.3 | 0.2353 | |
b-wave amplitude (µV) | 377.9 ± 47.4 | 457.3 ± 34.2 | 0.0667 | |
LA—30 Hz | Latency (ms) | 39.6 ± 6.9 | 47.3 ± 6.9 | 0.2107 |
Amplitude (µV) | 89.2 ± 11.5 | 91.6 ± 9.1 | 0.7740 | |
LA—3.0 | a-wave implicit time (ms) | 17.4 ± 0.3 | 18.0 ± 0.4 | 0.1107 |
a-wave amplitude (µV) | 27.1 ± 3.7 | 28.8 ± 1.5 | 0.6047 | |
b-wave implicit time (ms) | 34.0 ± 0.5 | 34.4 ± 0.6 | 0.3966 | |
b-wave amplitude (µV) | 107.6 ± 15.6 | 111.5 ± 9.1 | 0.6936 |