Correlation between hyperreflective foci and visual function testing in eyes with intermediate age-related macular degeneration

Table 2 Linear mixed effects models comparing the visual function metrics between the HRF and no-HRF group

Metric	Adjusting for cube-root transformed drusen volume			Adjusting for VA
Metric	HRF: yes vs. no	95% CI	P value	HRF: yes vs. no	95% CI	P value
VA	-9.36	-16.52, -2.19	0.011	-	-	-
LLVA	-9.88	19.40, -0.36	0.042	-7.24	-12.0, -2.44	0.003
LLD	1.35	-4.71, 7.42	0.662	7.24	2.44, 12.04	0.003
qCSF	-0.19	-0.48, 0.11	0.215	-0.15	-0.30, 0.00	0.054
LLqCSF	-0.2	-0.34, -0.06	0.005	-0.08	-0.15, -0.01	0.023
LLDqCSF	-0.26	-0.49, -0.04	0.023	-0.05	-0.16, 0.06	0.399
MAIA	-4.08	-8.14, -0.02	0.049	-3.05	-5.72, -0.39	0.025

HRF = hyperreflective foci. VA = visual acuity. LLVA = low luminance visual acuity. LLD = low luminance deficit. qCSF = quantitative contrast sensitivity function. LLqCSF = low luminance quantitative contrast sensitivity function. LLDqCSF = low luminance deficit quantitative contrast sensitivity function. MAIA = average MAIA perimetry sensitivity in dB. P values in bold are statistically significant

ISSN: 2056-9920