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Table 2 Demographic, clinical and optical coherence tomography (OCT) finding comparisons at the time of treatment advice between the two study groups:

From: REal-world treatment outcomes after delayed intRavitreal therapy in center-involving diabetic macular edema – RETORT study

 

Early treatment group

Delayed treatment group

P value

No of eyes (n)

94

15

 

No. of patients (n)

81

12

 

Males: Females (n)

63:18

9:3

> 0.999

Age (years)

65.93 ± 9.134

62.20 ± 9.536

0.148

Duration of DM (years)

16.99 ± 8.29

15.40 ± 5.06

0.795

HbA1c (%)

8.453 ± 1.03

8.213 ± 0.621

0.565

Moderate NPDR (n, %)

18 (20)

8 (53)

0.008

Severe NPDR (n, %)

38 (40)

0 (0)

0.001

PDR (n, %)

38 (40)

7 (47)

0.779

Visual acuity (ETDRS letters)

50.05 ± 12.1

58.23 ± 11.1

0.314

Central subfield thickness (microns)

527.2 ± 143.7

445.3 ± 107.8

0.036

Average time interval between recommending treatment and receiving treatment (weeks)

2.237 ± 3.607

31.24 ± 7.456

 
  1. Abbreviations: DM – diabetes mellitus; HBA1C - glycosylated hemoglobin; NPDR – non-proliferative diabetic retinopathy; PDR – proliferative diabetic retinopathy; ETDRS – Early Treatment Diabetic Retinopathy Study; DME – diabetic macular edema