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Table 3 Demographic, clinical and optical coherence tomography (OCT) finding comparisons between the two study groups at the time of injection and at 1 year post commencement of treatment:

From: REal-world treatment outcomes after delayed intRavitreal therapy in center-involving diabetic macular edema – RETORT study

 

Early treatment group

(n = 94)

Delayed treatment group

(n = 15)

P value

Worsening in DR severity at least by 1 step at the end of 1 year (n, %)

13 (14)

4 (27)

0.247

Mean VA (ETDRS letters) at the time of injection

49.74 ± 16.3

56.27 ± 15.2

0.003

Mean CSFT at the time of injection

527.2 ± 143.7

462.5 ± 73.57

< 0.001

Mean VA (ETDRS letters) 1-year after treatment

57.38 ± 20.01

51.4 ± 12.67

0.170

Mean change in VA (ETDRS letters) at the end of 1 year

7.638 ± 17.96

-6.867 ± 11.65

0.001

Mean CSFT 1-year after treatment

422.6 ± 158.9

477.8 ± 92.94

0.846

  1. Abbreviations: DR – diabetic retinopathy; VA – visual acuity; CSFT – central subfield thickness; ETDRS – Early Treatment Diabetic Retinopathy Study