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Table 2 Systemic manifestations of Dengue, Zika and Chikungunya

From: Arboviruses and the eye

Symptoms

Dengue

Zika

Chikungunya

Fever

High

Mild or absent

High

Pain

Muscle, joints, head and behind the eyes

Mild joint pain and edema

Severe joint pain and edema

Skin rash

Not associated with itchiness

Associated with itchiness

Associated with itchiness

Complications

Multiple organ failure: lungs, heart, liver, kidneys, central nervous system

Neurologic complications: muscle weakness, Guillan Barré syndrome

Chronic joint pain