Table 1 Prevalence and relative risk of inherited thrombophilia in the general population [9,10,11,12]
From: Choroidal infarction following ophthalmic artery chemotherapy
Coagulation disorder | Prevalence in the general population (%) | Relative risk of venous thromboembolism |
|---|---|---|
Anti-phospholipid syndrome | 5–10 | 5–10 |
Hyperhomocysteinemia (MTHFR homozygote) | 11 | 2.5 |
Factor V Leiden (heterozygote) | 5 | 6–8 |
Prothrombin G20210A mutation (heterozygote) | 2.3 | 2.8 |
Protein S deficiency | 1.3 | 2.4 |
Sickle cell trait | 1 | 1.5 |
Protein C deficiency | 0.2 | 6.5 |
Antithrombin deficiency | 0.02–0.04 | 17.5 |