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Table 1 Prevalence and relative risk of inherited thrombophilia in the general population [9,10,11,12]

From: Choroidal infarction following ophthalmic artery chemotherapy

Coagulation disorder Prevalence in the general population (%) Relative risk of venous thromboembolism
Anti-phospholipid syndrome 5–10 5–10
Hyperhomocysteinemia (MTHFR homozygote) 11 2.5
Factor V Leiden (heterozygote) 5 6–8
Prothrombin G20210A mutation (heterozygote) 2.3 2.8
Protein S deficiency 1.3 2.4
Sickle cell trait 1 1.5
Protein C deficiency 0.2 6.5
Antithrombin deficiency 0.02–0.04 17.5