Table 2 Risk factors for the development of retinopathy of prematurity (ROP) with indication for treatment
From: Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study
Risk factors | With type 1 prethreshold ROP | Without type 1 prethreshold ROP | P |
|---|---|---|---|
n = 30 (5%) | n = 572 (95%) | ||
Male, n (%) | 12 (40%) | 290 (50.7%) | .267a |
Type of birth, n (%) | .805a | ||
Singleton | 24 (80%) | 470 (82.5%)** | |
Twin or multiple | 6 (20%) | 100 (17.5%) | |
Sepsis, n (%) | 28 (96.6%)* | 424 (74.5%)*** | .004a |
Use of surfactants, n (%) | 29 (100%)* | 408 (71.6%)** | < .001a |
Intraventricular hemorrhage, n (%) | 9 (30%) | 95 (16.7%)** | .79a |
Erythropoietin, n (%) | 2 (6.7%) | 26 (4.6%)** | .644a |
Antenatal corticosteroids, N (%) | 8 (27.5%)* | 94 (16.5%)* | .211a |
Cardiac diseases, n (%) | 12 (40%) | 105 (18.4%) | .007a |
Pulmonary diseases, n (%) | 29 (96.7%) | 392 (68.5%) | < .001a |
Digestive diseases, n (%) | 3 (10%) | 24 (4.2%) | .146a |
Birth weight < 1000 g, n (%) | 18 (60.0%) | 130 (22.7%) | < .001a |
Gestational age (weeks), mean ± SD | 28.5 (2.6) | 31.8 (2.4) | < .001b |
Apgar score at 1 min, mean ± SD | 5.6 (2.43) | 6.5 (2.2) | .006b |
Apgar score at 5 min, mean ± SD | 7.2 (1.6) | 8.1 (1.4) | < .001b |
Days on oxygen therapy, median (minimum to maximum) | 41 (2–150) | 8 (0–150) | < .001c |
Days on CPAP, median (minimum to maximum) | 4 (0–42) | 2 (0–34) | < .001c |
Days on mechanical ventilation, median (minimum to maximum) | 16 (0–60) | 2 (0–150) | < .001c |
Number of blood transfusions, median (minimum to maximum) | 2 (0–15) | 1 (0–14) | < .001c |