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TableĀ 1 Stem cell therapy

From: Novel stem cell and gene therapy in diabetic retinopathy, age related macular degeneration, and retinitis pigmentosa

Condition Technique Result
Diabetic retinopathy Mesenchymal stem cells Absorption of ROS through expression of sulfoxide reductase A
Endothelial progenitor cells Incorporation into host retinal tissue and prevention of neovascularization
Macular degeneration Induction of pluripotent stem cells Differentiation into photoreceptors and RPE cells and integration into the host cell structure
Subretinal ESC transplantation Regenerative therapy
Retinitis pigmentosa Treatment with brain-derived neurotrophic factor Improved survival of neurons and retinal ganglionic cells and preserves structure of the optic nerve
Induction of neural stem cell secretion of ciliary neurotrophic factor Protection of photoreceptor cells