Fig. 5

The connection between Müller cells in the foveola and the middle part of lamellar macular hole-associated epiretinal proliferation (LHEP) at the inner surface of the foveal walls is visible only in certain orientations of SD-OCT scans. The images show radial scans through the fovea and parafovea in the left eye of a 77 year-old man. The orientations of the scans are shown at the left side. The arrowheads indicate LHEP. In the smaller images at the right side, the middle part of LHEP is indicated by yellow color, and cells of the Müller cell cone are indicated by green color. Note that there are no connections between Müller cells in the foveola and LHEP in the scans which show cavitations of the foveal pit into the lower foveal walls (scans 1‒3 and 6) whereas in the scans 4 and 5, foveal walls without cavitations display such connections. Scale bars, 200 µm. ELM: external limiting membrane; EZ: ellipsoid zone; GCL: ganglion cell layer; HFL: Henle fiber layer; INL: inner nuclear layer; IPL: inner plexiform layer; IZ: interdigitation zone; NFL: nerve fiber layer; ONL: outer nuclear layer; OPL: outer plexiform layer; RPE: retinal pigment epithelium