Macular edema after rhegmatogenous retinal detachment repair: risk factors, OCT analysis, and treatment responses

Table 1 Demographics, baseline characteristics, and surgical data of patients with aCME and nCME

	aCME	nCME	P value	Adjusted P value¹
Demographic data
Number of eyes	25 (25%)	74 (75%)
Follow-up (months)	21.4 ± 12.1	20.4 ± 10.8	0.87
Sex, Female	8 (32%)	38 (34%)	0.09
Age (years)	64.1 ± 11.6	56.7 ± 18.0	0.09
Clinical data
Right eye	11 (44%)	40 (54%)	0.38
Glaucoma	4 (16%)	6 (8%)	0.26
Lens status			< 0.001	0.008
Phakic	1 (4%)	44 (60%)
Pseudophakic	14 (56%)	28 (38%)
Aphakic	10 (40%)	2 (3%)
Macula off^a	20/24 (83%)	31/70 (44%)	0.001	0.06
PVR Stage C^a	15/24 (63%)	5/74 (7%)	< 0.001	0.09
Final VA (LogMAR)	0.85 ± 0.80	0.20 ± 0.30	< 0.001	0.012^b
ERM	18 (72%)	28 (38%)	0.005
Surgical details
Number of surgeries	3.5 ± 1.8	1.4 ± 0.9	< 0.001
Multiple PPV	21 (84%)	17 (23%)	< 0.001	–^c
Referred after surgery elsewhere	12 (48%)	5 (7%)	< 0.001	0.31
Number of surgery outside	1 ± 1.3	0.095 ± 0.4	< 0.001
Type of surgery			< 0.001	0.21
SB	1 (4%)	25 (34%)
PPV	7 (28%)	28 (38%)
PPV + SB	17 (68%)	21 (28%)
Tamponade agent			< 0.001	0.10
None/Air	1 (4%)	24 (32%)
Gas (SF₆ or C₃F₈)	8 (32%)	46 (62%)
Silicone oil	16 (64%)	4 (5%)
Cryotherapy^a	4/24 (17%)	30/73 (41%)	0.047	0.036
Retinectomy	9 (36%)	4 (5%)	< 0.001	0.009
PFCL^a	18/23 (78%)	35/47 (75%)	0.73	0.38

aCME all (chronic + transient) cystoid macular edema, nCME no cystoid macular edema, PVR proliferative vitreoretinopathy, VA visual acuity, LogMAR (logarithm of the minimum angle of resolution), PPV pars-plana vitrectomy, ERM epiretinal membrane, SB scleral buckle, PFCL perfluorocarbon liquid
^aDenominators are provided if the number is less than the total number of eyes in the category due to missing or incomplete data
^bFinal VA adjusted P value from a model with covariates for total number of surgeries and Macula on/off
^cAdjusted model not possible due to collinearity of Multiple PPV with number of surgeries (i.e. those with Multiple PPV had greater than 2 surgeries, while those with no PPV had fewer)
¹P-value for difference after adjustment for total number of surgeries

ISSN: 2056-9920