Fig. 3
From: Near-infrared reflectance imaging of neovascularization in proliferative diabetic retinopathy
Sequence of NVD over 4 years showing reactivation and subsequent regression. Baseline NIR a shows an inactive NVD with hyperreflective fibrotic component (✱). Note reactivation in the NIR image b with the development of new vascular hyporeflective dark fronds (box) and matching color fundus photograph c where the vascular component is easily identified (box). After panretinal photocoagulation, there is some involution of the nasal neovascular tissue, albeit with progression at the level of the arrow (d). With continuation of laser treatment, there is regression of the neovascular complex (e–f), shown by reduced dark perfusion. In f there is only hyperreflective avascular fibrotic tissue (✱) and no leakage on fluorescein angiography (g)