Fig. 2

Main DME: a–c Right eye of a 46-year-old patient with VA of 20/32. The thickness map shows an diffuse main DME involving more than three fields. However, the temporal retinal thickening widely overflowed the ETDRS grid, and the highest point is located in the ETDRS grid. B-scan shows an intermediate cyst in the foveola and small cysts with temporal retinal thickening and hard exudates. We also noted the presence of microaneurysm that are located outside the ETDRS grid and that could be targeted using focal laser. d–f Left eye of a 69-year-old patient with VA of 20/40. Thickness map shows an diffuse DME associated with three more peripheral retinal edemas, which are detected outside the ETDRS area. They are classified as peripheral retinal edemas as the peak is located outside the ETDRS grid even if they overflow into the ETDRS area. B-scan shows foveolar involvement and the presence of intermediate cysts with hard exudates and microaneurysms. We also noted the presence of intermediate cysts, hard exudates, and microaneurysms in the peripheral retinal edema in the same way as the main DME