Time point | CMTa (Mean ± SD) | Change from Baseline (Mean ± SD) | Change from Baseline (%) | P-valueb | 95% CI | |
---|---|---|---|---|---|---|
Lower | Upper | |||||
Baseline | 387 ± 99 |  |  |  |  |  |
Month 1 | 326 ± 90 | − 64 ± 75 | 15 |  < 0.0001 | 85 | − 43 |
Month 3 | 345 ± 88 | − 42 ± 85 | 8 | 0.002 | − 66 | − 18 |
Month 6 | 341 ± 96 | − 47 ± 69 | 11 |  < 0.0001 | − 66 | − 28 |
Month 12 | 342 ± 96 | − 46 ± 99 | 9 | 0.001 | − 73 | − 18 |