Table 3 Mean retinal layer thickness in T2D and controls
Retinal Layer Thickness, ETDRS (μm) | T2D | Controls | 95%CI | p-value |
|---|---|---|---|---|
(n = 258 eyes of 129 subjects) MD ± SD | (n = 74 eyes of 37 subjects) MD ± SD | |||
Retina | ||||
Center Retinal Thickness (CRT) | 237.8 (± 2.6) | 252.6 (± 4.8) | − 24.5 to − 4.9 | 0.003 |
Total Volume | 7.9 (± 0.04) | 8.1 (± 0.1) | − 0.4 to − 0.1 | 0.002 |
Inner Temporal (IT) | 293.1 (± 1.7) | 307.9 (± 3.5) | − 17.3 to − 2.4 | 0.010 |
Inner Superior (IS) | 309.9 (± 1.7) | 321.6 (± 3.1) | − 18.6 to − 4.9 | 0.001 |
Inner Nasal (IN) | 309.1 (± 1.9) | 322.2 (± 3.0) | − 19.6 to − 6.5 | 0.000 |
Inner Inferior (II) | 307.2 (± 1.7) | 319.9 (± 2.7) | − 18.6 to − 6.8 | 0.000 |
GCL+ | ||||
Total | 70.4 (± 0.6) | 73.8 (± 1.0) | − 5.6 to − 1.2 | 0.003 |
Temporal Superior (TS) | 70.5 (± 0.6) | 74.0 (± 1.5) | − 6.6 to − 0.5 | 0.024 |
Superior (S) | 69.7 (± 0.6) | 73.3 (± 1.1) | − 5.9 to − 1.2 | 0.003 |
Nasal Superior (NS) | 73.5 (± 0.6) | 76.6 (± 1.0) | − 5.4 to − 0.9 | 0.007 |
Nasal Inferior (NI) | 71.4 (± 0.7) | 75.0 (± 1.0) | − 6.0 to − 1.2 | 0.003 |
Inferior (I) | 66.6 (± 0.6) | 69.6 (± 1.1) | − 5.4 to − 0.5 | 0.017 |
Temporal Inferior (TI) | 71.0 (± 0.6) | 74.46 (± 1.2) | − 6.0 to − 1.0 | 0.007 |
RNFL | ||||
Total | 105.5 (± 1.0) | 110.0 (± 1.4) | − 7.9 to − 1.3 | 0.007 |
Temporal (T) | 74.6 (± 1.0) | 79.2 (± 1.5) | − 8.2 to − 1.0 | 0.014 |
Temporal Superior (TS) | 136.6 (± 1.8) | 146.1 (± 2.9) | − 16.3 to − 2.9 | 0.005 |
Nasal Superior (NS) | 122.1 (± 1.9) | 120.8 (± 4.0) | − 7.2 to 9.9 | 0.760 |
Nasal (N) | 88.9 (± 1.2) | 92.7 (± 2.2) | − 8.7 to 1.1 | 0.132 |
Nasal Inferior (NI) | 137.1 (± 2.4) | 140.0 (± 3.9) | − 12.0 to 6.2 | 0.534 |
Temporal Inferior (TI) | 140.8 (± 1.9) | 149.8 (± 2.8) | − 15.7 to − 2.3 | 0.008 |