Table 2 Injections and planned/observed treatment regimen (FAS)
Treatment-naïve (n = 181) | Previously treated (n = 77) | Overall (n = 258) | |
|---|---|---|---|
Planned treatment regimen | |||
T&E from initial treatment | 29 (16.0) | 10 (13.0) | 39 (15.1) |
5 initial monthly injections followed by T&E | 39 (21.6) | 18 (23.4) | 57 (22.1) |
5 initial monthly injections followed by injections every other month | 4 (2.2) | 0 | 4 (1.6) |
Treat until dry followed by T&E | 20 (11.1) | 11 (14.3) | 31 (12.0) |
Treat until dry followed by PRN | 42 (23.2) | 13 (16.9) | 55 (21.3) |
PRN from initial treatment | 28 (15.5) | 19 (24.7) | 47 (18.2) |
Other | 19 (10.5) | 6 (7.8) | 25 (9.7) |
Reported treatment regimena | |||
T&E | 25 (13.8) | 10 (13.0) | 35 (13.6) |
5 initial monthly injections followed by T&E | 13 (7.2) | 6 (7.8) | 19 (7.4) |
Treat until dry followed by T&E | 17 (9.4) | 10 (13.0) | 27 (10.5) |
Treat until dry followed by PRN | 60 (33.2) | 11 (14.3) | 71 (27.5) |
PRN from initial treatment | 29 (16.0) | 21 (27.3) | 50 (19.4) |
No initial treatment | 10 (5.5) | 7 (9.1) | 17 (6.6) |
Other | 27 (14.9) | 12 (15.6) | 39 (15.1) |
Mean IVT-AFL injections by Month 6 (mean ± SD) | 2.9 ± 1.2 | 3.2 ± 1.6 | 3.0 ± 1.3 |
Mean IVT-AFL injections by Month 12 (mean ± SD) | 3.7 ± 1.8 | 4.0 ± 2.2 | 3.8 ± 1.9 |
≥ 5 injections within 6 months | 13 (7.2) | 19 (24.7) | 32 (12.4) |
≥ 8 injections within 12 months | 7 (3.9) | 7 (9.1) | 14 (5.4) |