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Table 4 Multivariate logistic regression analysis of variables associated with the development of PSCR among patients with SCR

From: Risk factors associated with sickle cell retinopathy: findings from the Cooperative Study of Sickle Cell Disease

PSR

n = 423

OR

95% CI

P-value

Age at entry (years)

1.06

1.04, 1.08

 < 0.001

Eye symptoms

1.68

1.08, 2.62

0.021

Hemoglobin (g/dl)

1.29

1.14, 1.47

 < 0.001

WBC (109/L)

1.11

1.03, 1.19

0.004

Reticulocytes (%)

0.96

0.91, 0.99

0.050

HbF (%)

0.90

0.85, 0.94

 < 0.001

  1. SCR sickle cell retinopathy, PSCR proliferative sickle cell retinopathy, OR odds ratio, CI Confidence interval, WBC white blood cells, HbF hemoglobin F