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Table 3 Factors affecting mean improvement of central subfield thickness and best corrected visual acuity after the treatment

From: Effect of age on response to anti-VEGF agents in patients with center involving diabetic macular edema in a tertiary hospital

Factor

Post–pre CSTa

Post–pre BCVAb

Mean

p-value

Mean

p-value

Gender

    

 Male

 − 101.75

0.5542

4.04

0.1910

 Female

 − 112.08

7.07

Age

    

 ≤ 60 years

 − 125.1

0.0876

5.64

0.5429

 > 60 years

 − 94

5.49

DRIL

    

 Absent

 − 95.98

0.0031

5.20

0.2941

 Present

 − 156.42

7.13

HRF

    

 Absent

 − 89.70

0.4170

3.64

0.4426

 Present

 − 110.12

5.91

SRF

    

 Absent

 − 97.04

0.0053

4.41

0.0089

 Present

 − 166.13

12.43

Pr loss

    

 Absent

 − 93.96

0.0037

5.59

0.9230

 Present

 − 144.65

5.35

Focal Laser

    

 Absent

 − 108.44

0.7805

6.08

0.4281

 Present

 − 102.27

3.94

HTN

    

 Absent

 − 95.7143

0.7434

3.5429

0.5123

 Present

 − 109.2

5.9543

 

DLP

    

 Absent

 − 132.2

0.3530

5.9231

0.9202

 Present

 − 103.3

5.5000

 

IHD

    

 Absent

 − 112.7

0.1848

6.5549

0.0825

 Present

 − 79.8108

0.8649

 
  1. aBCVA, best-corrected visual acuity
  2. bCST, central subfield thickness; < 60 years, patients who are 60 years or younger; > 60 years, patients who are older than 60 years; DRIL, disorganization of retinal layers; HRF, hyperreflective foci; SRF, subretinal fluid; Pr loss, photoreceptors loss; focal laser, focal laser performance, HTN, hypertension; DLP, dyslipidemia; IHD, ischemic heart disease