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Table 4 Proposed CLOSE Study Group Surgical Classification for Macular Holes Based on the Minimum Linear Diameter (µm), Hole-Edge Configuration, Presence/Absence of Edematous Hole Edges, Macular Hole Index, Presence of Vitreomacular Traction, and Epiretinal Membrane

From: Surgical classification for large macular hole: based on different surgical techniques results: the CLOSE study group

Group

Hole Size (MLD) (µm)

Hole-edge configuration

edematous edges

MHI (Height/BLD)

VMT

ERM

VMT

  

Focal/ Diffuse

 

 Small

 < 250

Cuff or flat

Yes/no

 

Yes/no

Yes/no

 Medium

 > 250 to ≤ 400

Cuff or flat

Yes/no

 

Yes/no

Yes/no

 Large

 > 400 to ≤ 550

Cuff or flat

Yes/no

 

Yes/no

Yes/no

 X-Large

 > 550 to ≤ 800

Cuff or flat

Yes/no

 

Yes/no

Yes/no

 XX-Large

 > 800 to ≤ 1000

Cuff or flat

Yes/no

 

Yes/no

Yes/no

 Giant

 > 1000

Cuff or flat

Yes/no

 

Yes/no

Yes/no

  1. MLD minimum linear diameter, MHI macular hole index, BLD base linear diameter, cuff = separation of photoreceptors at hole edges from the retinal pigment epithelium (RPE) with difference between MLD and BLD ≥ 200 µm; flat no separation of photoreceptors from RPE or minimal separation with difference between MLD and BLD < 200 µm; edematous edges  presence of multiple cystoid cavities at hole edges; VMT vitreomacular traction; focal ≤ 1500 µm; diffuse   > 1500 µm; ERM epiretinal membrane