Fig. 2

A Top left. The color fundus photo of the right eye of a 16-year-old female with a history of MFC. The macular area shows a well-circumscribed area of neurosensory detachment approximately 2-disc diameter in size (arrows) with a central subretinal yellowish-white lesion and a meniscus of SRH. Top right. SS-OCT of the same eye in a line scan mode shows diffuse macular thickening (spongy edema), multiple intra-retinal hyperreflective foci, a sub-foveal amorphous hyperreflective lesion above the RPE with surrounding neurosensory detachment and overlying turbid SRF. Bottom. SS-OCTA image in a 3 × 3 mm field of the outer retina and the corresponding flow density map. Note the hyperintense signal with dense arborization, vascular anastomosis, and looping that are characteristic of a large active neovascular network. Note the high flow within the neovascular network in the flow density map. B Top left. The color fundus photo of the same eye 6 months after 3 IVA injections. The macular area shows resolution of neurosensory detachment, and SMH, which are replaced by a well-circumscribed submacular yellowish elevated lesion consistent with scar formation. Top right. SS-OCT in a line scan mode shows a subfoveal dome-shaped hyperreflective lesion above the RPE with the resolution of the previously noted spongy edema, neurosensory detachment, and SRF. Bottom. SS-OCTA image in a 3 × 3 mm field of the outer retina and the corresponding flow density map. Note the low-intensity signal within residual filament-like vascular channels, and significantly lower flow in the flow density map compared to the baseline