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Table 3 OCT biomarkers of diabetic macular edema (DME) eyes at baseline and at 1 month and 4 months after dexamethasone implant

From: OCT biomarkers as predictors of visual improvement in diabetic macular edema eyes receiving dexamethasone implants

 

Baseline (n = 33)

1 month (n = 33)

4 months (n = 33)

p-value

CST µm, mean ± SD

487.0 ± 142.0

318.4 ± 61.7

389.3 ± 129.6

< 0.001°

CAT-3 mm µm, mean ± SD

448.6 ± 97.7

357.3 ± 42.2

378.5 ± 99.1

< 0.001°

CV-3 mm mm3, mean ± SD

3.17 ± 0.72

2.53 ± 0.30

2.73 ± 0.53

< 0.001°

SND, n (%)

9 (27.2%)

4 (12.1%)

8 (24.2%)

0.298*

ICS > 200 μm, n (%)

32 (96.9%)

19 (57.6%)

22 (66.6%)

< 0.001*

DRIL, n (%)

10 (30.3%)

14 (42.4%)

9 (27.2%)

0.492*

SHF, n (%)

19 (57.6%)

21 (63.6%)

22 (66.6%)

0.811*

HF, n (%)

28 (84.8%)

30 (90.9%)

27 (81.8%)

0.572*

EZ/ELM alteration, n (%)

19 (57.6%)

23 (69.7%)

17 (51.5%)

0.359*

VMT, n (%)

6 (18.2%)

7 (21.2%)

9(27.2%)

0.755*

  1. CAT: cube average thickness, CST: central subfoveal thickness, CV: cube volume, DRIL: disorganization of the inner retinal layers, EZ/ELM: ellipsoid zone/ external limiting membrane, ICS: Intraretinal Cystoid Spaces, IOP: intraocular pressure, HF: hyperreflective foci, SHF: Subfoveal hyperreflective foci, SND: Subfoveal neuroretinal detachment, VMT: vitreomacular traction. *Fischer’s exact test. °Unpaired t-test