Table 3 Subretinal device characteristics
Device | Electrode specifications | Size | Advantages | SAE/AEs | Clinical status |
|---|---|---|---|---|---|
PRIMA | 378 electrodes (100 µm in width) | 2 × 2 mm and 30 microns thick | - May result in natural conversion of pulsed spatiotemporal stimulation pattern into bursts of spikes from the retinal ganglion cells - Minimally invasive procedure - Targeted electrical stimulation | - Reduced retinal thickness | In clinical trial for age-related macular degeneration (France and USA) |
IMTC’s HARP4k retinal prosthesis system | 4000 microelectrodes (30 µm thick) | 30 mm | - Contact lens shape | Information not available | Designed for retinitis pigmentosa and age-related macular degeneration |
- Wireless | |||||
- Expected to support face recognition and reading font size > 14 pt | |||||
- High granularity and efficiency | |||||
- Biocompatible and implantable | |||||
- Flexible technology interfacing soft tissue |