Table 5 Neural device characteristics
Device | Electrode specifications | Size | Advantages | SAE/AEs | Clinical Status |
|---|---|---|---|---|---|
ORION | 60 electrodes | Information not available | - Treats a wider variety of diseases - Neural placement - Ability to navigate the environment | - Seizure - Bilateral Hand twitch - Headache - Visual Aura - Visual Phenomenon | Ongoing clinical trials evaluating the safety of the device and surgery |
CORTIVIS | 100 electrodes (1.0–1.5 mm in length) | 4 mm x 4 mm base | Information not available | Information not available | In clinical trial for severe visual impairment with bilateral visual loss |
ICVP | 16 electrodes per module | 2Â mm x 2Â mm | - No wires or connectors cross the scalp due to wireless nature - Camera images are communicated directly to brain | Information not available | In clinical trials to test the safety of the ICVP system and the feasibility of eliciting visual percepts in response to electrical stimulation in persons with blindness |
AV-DONE | 7 stimulation electrodes (50 µm diameter) | - The rod: 100 μm diameter - Cylindrical silicone board diameter: 2.0 mm. of the active tips of the stimulation electrodes is uncoated. The wires run parallel to each other. Scale bar = 1 mm | - Easy access to the optic nerve - Stimulate a wide visual field - Elicit small to large phosphenes using just one stimulating electrode | Information not available | Clinical study completed for 1 patient with RP |