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Table 3 Complications related to ERM removal in the included studies

From: Surgical management, use and efficacy of adjuvant dyes in idiopathic epiretinal membranes: a systemic review with network meta-analysis

References

Study design

Type of surgery

Adjuvant dye(s)

Complications

Ehlers et al. [34]

Prospective interventional

PPV with ERM peeling with optional ILM peeling at surgeon's discretion

ICG and/or TA

Cataract progression (3/52 phakic patients) RD (1/76)

Hillenkamp et al. [19]

RCT

PPV with ERM peeling with versus without ICG

ICG

RD (2/27 in ICG; 1/32 in without ICG group) paracentral, lower nasal visual field defect (2/27 in ICG group)

Jonna et al. [36]

Prospective interventional

PPV with ERM peeling

ICG and/or TA at surgeon's discretion

PVD (5/20) ocular hypertension (1/20)

Shahzadi et al. [33]

Prospective interventional

PPV with ERM peeling

None

RD (1/30) CME (1/30)

Sola et al. [21]

RCT

PPV with ERM peeling only versus ERM with ILM peeling

TB for ERM and BBG for ILM

Intraoperative retinal breaks (1/26) CME with subsequent ocular hypertension (2/26) nonarteritic anterior ischemic optic neuropathy (1/26)

Mackenzie et al. [30]

Prospective nonrandomized comparative

PPV with ERM peeling with stain versus without stain

TB 0.15%

Mild retinal hemorrhage 3/16 in stained and 8/18 nonstained participants retinal breaks 1/18 nonstained participants

  1. BBG, Brilliant Blue G; CME, cystoid macular edema; ERM, epiretinal membrane; ICG, indocyanine green; PPV, par plana vitrectomy; PVD, posterior vitreous detachment; RCT, randomized controlled trial; RD, retinal detachment; TA, triamcinolone acetonide; TB, trypan blue