Fig. 2

Selection of patients for control and case groups. Abbreviations: ICD-10, International Classification of Diseases 10th edition; MH macular hole, ERM Epiretinal membrane, OCT Optical coherence tomography, EZ Ellipsoid zone, RPE Retinal Pigment Epithelium, RD Retinal detachment, CSCR Central serous chorioretinopathy. Advanced retinopathy was defined as intermediate-stage or worse age-related macular degeneration, moderate-stage or worse diabetic retinopathy, glaucoma, retinal vein/artery occlusions and retinal dystrophies. High myopia was defined as the spherical equivalent of ≥ − 6.00 diopters or axial length of ≥ 26.5 mm. Structural abnormalities excluded were abnormal foveal contours, ellipsoid zone disruption, retinal pigment epithelium irregularity, or choroidal thickening