Fig. 1
From: Serous maculopathy with absence of retinal pigment epithelium (SMARPE) associated with large drusen
Multimodal imaging in a 75-year-old woman (Case # 1) presenting with bilateral serous maculopathy with absence of retinal pigment epithelium (SMARPE). Visual acuity was 20/150 in the right eye and 20/200 in the left eye. Color fundus photograph of both eyes (A and E) shows several typical age-related macular degeneration (AMD) large drusen and retinal pigment epithelium (RPE) atrophy within the macular area, with correspondent hypoautofluorescence on fundus autofluorescence (FAF) (B and F), and hyperfluorescence due to window defect on fluorescein angiography (FA) (C and G). Cross-sectional spectral-domain optical coherence tomography (SD-OCT) of both eyes (D and H) depicts the incomplete type (asterisks) of SMARPE (there is part of the RPE between the SRF edges) in the macular area. An intact ellipsoid zone (EZ) and external limiting membrane (ELM) overlying the RPE defect are observed in both eyes