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Table 1 Baseline characteristics of the included patients with RD or RB

From: Surgical management of retinal detachment and macular holes secondary to ocular toxoplasmosis: a systematic review and meta-analysis

Study (year)

Design

Number of patients

M/F ratio

Mean age

Associated Pathologies

Follow-up

Worsening in visual acuity

Number of RD or RB

Retinal Reattachment

Type of RD or RB

Intervention

Clinical Treatment

Moreira (2018)

Retrospective

22

13/9

28.5

Proliferative Vitreoretinopathy (5/22);

64.9 months

2

22

20/22

RRD (22/22)

RSB (4/22); PPV + GAS(1/22); PPV + SO(4/22); RSB + GAS (3/10); RSB + PPV + SO (10/22)

NA

Lucena (2009)

Retrospective

10

3/7

38

NA

NA

3

10

10/10

RD + RR (8/10); RRP (retinal rupture) (2/10)

Retinopexy + PPV (2/10); PPV (4/10); Retinopexy (2/10); Laser (2/10)

NA

Kianersi (2012)

Retrospective

5

1/4

27

NA

1 month

5

5

5/5

RRD (3/5) + TRD (1/5) + Unknow URD (1/5)

PPV + lensectomy(1/5); SB + Crypexia (1/5); SB (2/5); PPV + SO(1/5)

Antiparasitics with corticosteroids (oral and topical), mydriatic agents (4/5); None (1/5)

Faridi (2015)

Retrospective

28

14/14

40

NA

22.5 months

3

4

4/4

RRD (4/4)

PPV + PFO + MP + AFX + EL + SO—> PPV/ROSO/PPL/MP/EL/retinectomy/SB/C3F8—> PPV/MP/EL/PFO/300° retinectomy/AFX/long-acting SO tamponade (1/4); PPV/AFX/EL/SF6—> PPV/EL/AFX/SB/SF6—> PPV/retinectomy/PFO/AFX/EL/SO/CE IOL/PPV/ROSO—> PPV/270° retinectomy/AFX/EL/ long-acting SO tamponade—> PPV/ROSO/MP; PPV/AFX/EL/MP/SO (1/4); Laser retinopexy (1/4)

Oral Antibiotic therapy [sulfamethoxazole/trimethoprim (9/28), triple therapy: sulfadiazine, pyrimethamine, and folinic acid, (6/28), clindamycin (3/28), or azithromycin (1/28), unknown (9/28)]; Intravitreal Therapy [intravitreal clyndamicin and dexamethasone (2/4), intravitreal clyndamicin and triamcinolone (1/4), intravitreal triamcinolone (1/4)]

Driessen (2000)

Retrospective

150

NA

29.5

Myopia + RB/RD (8/16); Myopia (35/134)

7 years

7

16

12/16

RD (8/16); RD + RB(1/16); RB (7/16)

SB + PPV + SO (1/16); SB (2/16); SB + lensectomy (1/16); Cryopexia + SB (1/16); PPV + SO + lensectomy (1/16); Cryocogulations 1/16 + Abstained (2/16); Laser coagulation (7/16)

Antiparasitics with corticosteroids (4/16); Antiparasitics (3/16); Corticosteroids (2/16); None (7/16)

Caplan (2023)

Retrospective

420

NA

40.9

Proliferative Vitreoretinopathy (4/13 RRD);

3 months

N/A

27 (16 analyzed)

14/14 (14 analyzed in last follow-up)

RRD (13/16); TRD (3/16)

SB + SO (2/14); PPV + SO (7/14); PPV + SB + SO (5/14)

NA

Adán (2009)

Retrospective

15

8/7

37.2

NA

41.4 months

0

8

8/8

RRD (6/8); RRD + TRD (2/8)

SB + PPV + SO (1/8); SB + PPV + delamination + GAS (1/8); SB + PPV + lensectomy + SO (2/8); SB + PPV + GAS (4/8)

Trimethoprim/sulfamethoxazole and oral prednisone at tapering doses for 30–40 days

Study (year)

Design

M:F

Age

Associated Pathologies

Follow- up

Worsening in visual acuity

Anatomical closure

Type of RD or RB

Intervention

Clinical Treatment

Scott (2018)

Case report

M

27

NA

5 months

YES

YES

Retinal tear + RRD

SB + PPV + GAS

Trimethoprim/sulfamethoxazole (160 mg/800 mg) twice daily and clindamycin 300 mg three times daily, as well as topical glucocorticoids and a mydriatic agent. One week later, he initiated systemic oral glucocorticoid therapy (prednisone 60 mg daily) with a scheduled taper

Erol (2021)

Case report

F

30

NA

2 months

YES

YES

MH + RD

PPV

Trimethoprim/sulfamethoxazole (160/800 mg) twice a day and clindamycin 300 mg four times a day. After three days, 32 mg/day methylprednisolone was added to oral treatment

  1. NA not available, PPV pars plana vitrectomy, RD retinal detachment, RRP retinal rupture, TRD tractional retinal detachment, URD unknown retinal detachment, RB retinal break, ILM internal limiting membrane peeling, ERM epiretinal membrane peeling, RSB retinopexy with scleral buckling, GAS gas infusion, SO silicone oil infusion; SB scleral buckling, RRD rhegmatogenous retinal detachment; MH macular hole, AFX air–fluid exchange, CE IOL cataract extraction with intraocular lens placement, EL endolaser, MP membrane pee, PFO perfluorocarbon, PPL pars plana lensectomy, ROSO removal of silicone oil