Recommendations for diabetic macular edema management by retina specialists and large language model-based artificial intelligence platforms

Table 1 ‘Majority’ responses by clinicians and AI platforms for individual case scenarios

Case	Eye	DME management		Ocular co-morbidity management
Case	Eye	Majority clinician response	Majority AI response	Majority clinician response	Majority AI response
1	RE	ML	OBS	OBS	OBS
1	LE	IVA	IVA	OBS	OBS
2	RE	ML	ML	PRP	PRP
2	LE	ML	ML	PRP	PRP
3	RE	OBS	OBS	OBS	OBS
3	LE	OBS	OBS	OBS	OBS
4	RE	OBS	OBS	OBS	OBS
4	LE	OBS	IVA	PRP	OBS
5	RE	OBS	OBS	OBS	OBS
5	LE	ML	ML	OBS	OBS
6	RE	OBS	OBS	OBS	OBS
6	LE	IVA	IVA	OBS	OBS
7	RE	IVA	IVA	OBS	CAT
7	LE	OBS	IVA	OBS	OBS
8	RE	IVS	IVA	PRP	OBS
8	LE	OBS	OBS	PRP	OBS
9	RE	ML	ML	OBS	OBS
9	LE	ML	ML	OBS	OBS
10	RE	IVS	IVA	OBS	OBS
10	LE	IVS	IVA	OBS	OBS
11	RE	OBS	OBS	OBS	OBS
11	LE	OBS	OBS	OBS	OBS
12	RE	IVA	IVA	OBS	OBS
12	LE	OBS	OBS	OBS	OBS
13	RE	OBS	OBS	OBS	OBS
13	LE	OBS	OBS	OBS	OBS
14	RE	OBS	OBS	OBS	OBS
14	LE	OBS	OBS	OBS	OBS
15	RE	IVA	IVA	OBS	OBS
15	LE	IVA	IVA	OBS	OBS
16	RE	IVS	ML	OBS	OBS
16	LE	OBS	OBS	OBS	OBS
17	RE	OBS	IVA	PRP	OBS
17	LE	OBS	OBS	PRP	PRP
18	RE	OBS	OBS	OBS	OBS
18	LE	OBS	OBS	OBS	OBS
19	RE	IVA	IVA	OBS	OBS
19	LE	IVA	IVA	OBS	OBS
20	RE	OBS	OBS	OBS	OBS
20	LE	OBS	OBS	OBS	OBS
21	RE	IVA	IVA	OBS	OBS
21	LE	OBS	OBS	OBS	OBS
22	RE	IVS	IVA	OBS	OBS
22	LE	OBS	OBS	OBS	OBS
23	RE	IVA	IVA	OBS	OBS
23	LE	IVA	IVA	PRP	CAT
24	RE	OBS	OBS	OBS	OBS
24	LE	OBS	OBS	OBS	OBS
25	RE	IVA	IVA	OBS	OBS
25	LE	IVA	IVA	OBS	OBS

Abbreviations: AI– artificial intelligence; DME– diabetic macular edema; RE– right eye; LE– left eye; OBS– observation; ML– macular laser; IVA– intravitreal antiVEGF; IVS– intravitreal steroid; PRP– pan retinal photocoagulation; CAT– cataract surgery

ISSN: 2056-9920