Fig. 1

Blue light autofluorescence (AF), fluorescein angiography (FA) and optical coherence tomography (OCT). Comparison of AF (A, B) and FA (C, D) with progressing diabetic retinopathy (DR) in 2010 (A, C) and 2019 (B, D), and OCT in 2010 (E) and 2019 (F). Bilateral areas of non-perfusion, microaneurysms, and dot blot haemorrhages along with the MacTel signs: loss of macular pigment (centrally increased FAF) and perifoveal telangiectasia with late leakage on FA, (C) in early phase within first 90 s, (D) in late phase after 6 min. OCT at presentation (E) with subfoveal outer retinal ellipsoid zone dehiscence and early temporal outer retinal degeneration with left early cystoid spaces. At final visit (F) advanced subfoveal outer retinal atrophy, ILM drape and temporal intraretinal fluid at right side, with less affected outer retinal temporal changes in left eye