Fig. 2

Blue light autofluorescence (AF) (A), confocal blue light reflectance (BLR) (B) and wide field fluorescence angiography (FA) (C, D) images taken at last follow up, with OCT at baseline (E) and last follow up (F). The AF (A) shows both increased and decreased central autofluorescence due to the loss of macular pigment in the parafoveal temporal area, intraretinal pigmentation and macular photoreceptor atrophy. Like case 1, signs of DR were very distinct as decreased AF. BLR (B) shows the disease specific oval shaped hyperreflectivity in the macular area, and also shows distinctly active NVE in the left eye. The wide field FA (C) shows parafoveal leakage typical for MacTel and leaking NV in the inferior temporal quadrant. Laser scars from previous PRP treatment are visible, FA taken after 2 min. OCT at baseline (E) with pronounced subfoveal and temporal outer retinal atrophy, and hyperreflective pigment clumping at last visit (F)