Articles

A Value-Based Medicine cost-utility analysis of genetic testing for neovascular macular degeneration

There is a dearth of patient, preference-based cost-effectiveness analyses evaluating genetic testing for neovascular age-related macular degeneration (NVAMD).

Authors: Gary C. Brown, Melissa M. Brown, Heidi B. Lieske, Philip A. Lieske and Kathryn S. Brown

Evaluation of retinectomy in the treatment of severe proliferative vitreoretinopathy

To evaluate the postoperative results and efficacy of retinectomy in the treatment of severe proliferative vitreoretinopathy (PVR).

Authors: Thaís Sousa Mendes, André Marcelo Vieira Gomes, Bruno Saraiva Rocha, Hélcio Valério Passos Junior and Suel Abujamra

Safe dose of intravitreal imatinib and its effect on laser-induced choroidal neovascularization: a rat-model experiment

This two-phase experimental study was conducted to determine the maximum safe dose of intravitreal imatinib (IVI) and its inhibitory effect on a rat model of choroidal neovascularization (CNV).

Authors: Homayoun Nikkhah, Hamid Ahmadieh, Alireza Ramezani, Mozhgan Rezaei Kanavi, Seyed Bagher Hosseini, Naficeh Sadeghi, Seyed Mohsen Khandaghy Meybodi and Mehdi Yaseri

Type 1 neovascularization may confer resistance to geographic atrophy amongst eyes treated for neovascular age-related macular degeneration

To report a series of age-related macular degeneration (AMD) patients in whom progression to geographic atrophy (GA) in one eye receiving frequent intravitreal injections of anti-vascular endothelial growth fa...

Authors: Elona Dhrami-Gavazi, Chandrakumar Balaratnasingam, Winston Lee and K. Bailey Freund

Multimodal imaging documentation of rapid evolution of retinal changes in handheld laser-induced maculopathy

To use multimodal imaging to document the relatively rapid clinical evolution of handheld laser-induced maculopathy (HLIM). To demonstrate that inadvertent ocular injury can result from devices mislabeled with...

Authors: Elona Dhrami-Gavazi, Winston Lee, Chandrakumar Balaratnasingam, Larisa Kayserman, Lawrence A. Yannuzzi and K. Bailey Freund

How to prevent endophthalmitis after intravitreal injections

Endophthalmitis is an uncommon but often visually devastating complication of intravitreal injections. This commentary reviews the key aspects and technical components of intravitreal injections and how they m...

Authors: Roger A Goldberg

Optic disc pit maculopathy: when and how to treat? A review of the pathogenesis and treatment options

Optic disc pit (ODP) is a rare congenital anomaly of the optic disc, which can be complicated by a maculopathy associated with progressive visual loss. Optic disc pits are usually unilateral and sporadic in oc...

Authors: Elad Moisseiev, Joseph Moisseiev and Anat Loewenstein

Optical coherence tomography angiography findings of choroidal neovascularization in pseudoxanthoma elasticum

Angioid streaks (AS) are the most common ocular manifestation in patients with pseudoxanthoma elasticum (PXE). The major cause of severe visual loss in patients with AS is choroidal neovascularization (CNV). W...

Authors: Orly Gal-Or, Chandrakumar Balaratnasingam and K Bailey Freund

High-resolution adaptive optics findings in talc retinopathy

Talc retinopathy is a recognized ocular condition characterized by the presence of small, yellow, glistening crystals found inside small retinal vessels and within different retinal layers. These crystals can ...

Authors: Mohamed K Soliman, Salman Sarwar, Mostafa Hanout, Mohammad A Sadiq, Aniruddha Agarwal, Vikas Gulati, Quan Dong Nguyen and Yasir J Sepah

Endophthalmitis following intravitreal anti-vascular endothelial growth factor (VEGF) injection: a comprehensive review

The purpose of this review is to report and summarize previously reported studies and assess many of the individual steps of the intravitreal injection procedure’s possible effect on the prevention of endophth...

Authors: Rohan Merani and Alex P Hunyor

Type 1 neovascularization with polypoidal lesions complicating dome shaped macula

Dome-shaped macula is described as an inward bulge of the macula within a posterior staphyloma in highly myopic eyes. Choroidal neovascularization is a known complication that can cause visual loss in dome-sha...

Authors: Jonathan Naysan, Kunal K Dansingani, Chandrakumar Balaratnasingam and K Bailey Freund

Low dose corticosteroid in association with methotrexate for therapy of ocular sarcoidosis: report of a case

Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Ocular involvement can be the initial manifestation, occurring by itself, or it can be associated with other systemic signs of sarcoidosi...

Authors: Grasiane Nunes Mayer, Morgana Longo, Bárbara Brandi Gomes and Mário Junqueira Nóbrega

Comparison of outcomes between 20, 23 and 25 gauge vitrectomy for idiopathic macular hole

To compare the results of 20, 23, 25 gauge pars plana vitrectomy (PPV) with two different gas tamponades for idiopathic macular hole (MH) in a multi-surgeon vitroretinal practice.

Authors: Fatma Dihowm and Mathew MacCumber

A review of optical coherence tomography angiography (OCTA)

Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging technique that generates volumetric angiography images in a matter of seconds. This is a nascent technology with a potential wide ...

Authors: Talisa E de Carlo, Andre Romano, Nadia K Waheed and Jay S Duker

Diabetes induces changes in neuroretina before retinal vessels: a spectral-domain optical coherence tomography study

To investigate retinal changes prior to vascular signs in patients with type 2 diabetes without diabetic retinopathy or with mild non proliferative diabetic retinopathy.

Authors: Eduardo Büchele Rodrigues, Müller Gonçalves Urias, Fernando Marcondes Penha, Emmerson Badaró, Eduardo Novais, Rodrigo Meirelles and Michel Eid Farah

Welcome to International Journal of Retina and Vitreous

Authors: Eduardo B Rodrigues, Jay S Duker and André V Gomes

Timing and outcomes after silicone oil removal in proliferative vitreoretinopathy: a retrospective clinical series

To evaluate anatomical and functional outcomes after silicone oil extraction in patients with retinal detachment and proliferative vitreoretinopathy in an eye care referral center in Joinville, SC, southern Br...

Authors: Renata Leite De Pinho Tavares, Mário Junqueira Nóbrega, Fernando Amaral Junqueira Nóbrega, Fernando José De Novelli and Carlos Augusto Cardim De Oliveira

Investigation of new dyes for chromovitrectomy: preclinical biocompatibility of trisodium, orangell and methyl violet

To investigate the retinal toxicity by electroretinography (ERG), clinical examination and histology after intravitreal injection of biological stains in two concentrations: Trisodium (0.50 g/L and 1.00 g/L), ...

Authors: Emmerson Badaro, Rodrigo A Souza-Lima, Eduardo A Novais, Mauricio Maia, Flávio Hirai, Carsten H Meyer, Michel Eid Farah and Eduardo B Rodrigues